Interesting comment, it is definitely something to consider. Thank you very much.marc108 wrote: for example: higher cholesterol could be indicative of higher meat consumption, which would give you more b12 and maybe the b12 is actually whats improving their psych scores. it could be that they have some genetic abnormality and the low cholesterol is just a symptom of that... kind of how the smoke alarm isnt actually a fire, just an indicator of the fire. it could be that when you spread this study out to 10,000 people instead of 20, this association disappears. its hard to know... i'm not saying its baseless, i'm just saying that assuming causal mechanisms in the way those blogs are is just bad science.
this was also a huge issue during some initial testing of vitamin supplements. for ex: we noticed people with high levels of blood vitamin A had less lung cancer. so the assumption was made that it was the vitamin A decreasing cancer... when the vitamin A is isolated and given to people, lung cancer actually increases! turns out that vitamin A is just an indicator for who's consuming more fruits and vegetables, and its the higher intake of fruits and veggies that actually is correlated with less lung cancer... through some unknown mechanism.
But cholesterol has many health benefits. Recent research revealed, for instance, that cholesterol plays a key role in regulating protein pathways involved in cell signaling and may also regulate other cellular processes.1
It’s already known that cholesterol plays a critical role within your cell membranes, but this new research suggests cholesterol also interacts with proteins inside your cells, adding even more importance.
Your body is composed of trillions of cells that need to interact with each other. Cholesterol is one of the molecules that allow for these interactions to take place. For example, cholesterol is the precursor to bile acids, so without sufficient amounts of cholesterol, your digestive system can be adversely affected.
It also plays an essential role in your brain, which contains about 25 percent of the cholesterol in your body. It is critical for synapse formation, i.e. the connections between your neurons, which allow you to think, learn new things, and form memories.
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If Cholesterol plays essential role in the brain, then it is likely that too little of it can have negative affects on the mood.